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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CKMT1A
All Species:
40.91
Human Site:
T268
Identified Species:
69.23
UniProt:
P12532
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12532
NP_001015001.1
417
47037
T268
W
V
N
E
E
D
H
T
R
V
I
S
M
E
K
Chimpanzee
Pan troglodytes
XP_517671
356
40461
E237
E
V
E
R
L
I
Q
E
R
G
W
E
F
M
W
Rhesus Macaque
Macaca mulatta
XP_001102013
767
82902
T618
W
V
N
E
E
D
H
T
R
V
I
S
M
E
K
Dog
Lupus familis
XP_535451
417
47057
T268
W
V
N
E
E
D
H
T
R
V
I
S
M
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P30275
418
46985
T269
W
V
N
E
E
D
H
T
R
V
I
S
M
E
K
Rat
Rattus norvegicus
P25809
418
47010
T269
W
V
N
E
E
D
H
T
R
V
I
S
M
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516190
602
66708
T268
W
V
N
E
E
D
H
T
R
V
I
S
M
E
K
Chicken
Gallus gallus
P70079
417
47085
T268
W
I
N
E
E
D
H
T
R
V
I
S
M
E
K
Frog
Xenopus laevis
NP_001080463
418
46838
T269
W
I
N
E
E
D
H
T
R
I
I
S
M
E
K
Zebra Danio
Brachydanio rerio
XP_002663507
417
46785
T268
W
V
N
E
E
D
H
T
R
V
I
S
M
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48610
356
39848
G237
I
I
S
M
Q
Q
G
G
D
L
G
Q
I
Y
K
Honey Bee
Apis mellifera
O61367
355
39990
G236
I
I
S
M
Q
M
G
G
D
L
G
Q
V
Y
R
Nematode Worm
Caenorhab. elegans
Q10454
396
44149
L269
W
C
N
E
E
D
H
L
R
I
I
S
M
Q
E
Sea Urchin
Strong. purpuratus
P18294
1174
130851
T1023
W
V
N
E
E
D
H
T
R
V
I
S
M
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.1
54.2
98.3
N.A.
96.6
95.9
N.A.
65.2
88.4
83
79.8
N.A.
37.8
37.4
38.6
24.4
Protein Similarity:
100
78.6
54.3
99.2
N.A.
98.3
97.8
N.A.
68.1
93
91.1
90.4
N.A.
54.9
55.1
53.7
30
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
100
93.3
86.6
100
N.A.
6.6
0
66.6
100
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
40
40
86.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
79
0
0
15
0
0
0
0
0
0
% D
% Glu:
8
0
8
79
79
0
0
8
0
0
0
8
0
72
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
15
15
0
8
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
79
0
0
0
0
0
0
0
0
% H
% Ile:
15
29
0
0
0
8
0
0
0
15
79
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
79
% K
% Leu:
0
0
0
0
8
0
0
8
0
15
0
0
0
0
0
% L
% Met:
0
0
0
15
0
8
0
0
0
0
0
0
79
8
0
% M
% Asn:
0
0
79
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
15
8
8
0
0
0
0
15
0
8
0
% Q
% Arg:
0
0
0
8
0
0
0
0
86
0
0
0
0
0
8
% R
% Ser:
0
0
15
0
0
0
0
0
0
0
0
79
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% T
% Val:
0
65
0
0
0
0
0
0
0
65
0
0
8
0
0
% V
% Trp:
79
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _